Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16156 | CA38451 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 22 |
| 2 | AZT+DDC | 26 |
| 3 | D4T | 74 |
| 4 | 3TC+D4T+IDV | 309 |
| 5 | 3TC+ABC+NVP | 42 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V | K219Q | Y181C | V108VI, V179VD | K32N, V35I, T69N, K101R, K103KR, I135K, G196E, L228H, V245I, K249R, S251H, K277R, A288T, V292I, I293V, E297K |
| >CA38451| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKINALIEICTELEKEGKISKIGPENPYNTPV FAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLRKRKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIDI CQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGFTTPDQKHQKEPPFHWMGYELHPDKWT VQPIILPERDHWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKTLTEIVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37E |
| >CA38450| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMELPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |