<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08PR060564 08PR060564 Brazil 2006 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   L10I, I13V, Q18L, K20T, E35D, M36I, R41K, R57K, Q61N, I62IV, L63S, I64IV, E65D, I72T, L89M  
>08PR060564| codons 1-99
PQITLWQRPIVTVKIGGLLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NVSVDICGHKATGTVLVGPTPVNIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V       V35T, T39E, S48T, V60I, D121H, K122E, D123E, D177E, Q197K, T200A, Q207D, V245T, D250E, A272P, R284RK, I293V, P294Q, V317VA, S322T, I329V  
>08PR060564| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGKHRAKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGTKALTEVVQLTEEAE
LELAENREILKEPVHGAYYDPTKDLIAEVQKQGQG

References
Author Title Citation
Waleria-Aleixo, A Drug resistance mutation profile and accumulation kinetics in human immunodeficiency virus-positive individuals infected with subtypes B and F failing highly active antiretroviral therapy are influenced by different viral codon usage patterns. AAC, 2008