<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08PR050350 08PR050350 Brazil 2005 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  Q58E L33V, N37S, R41K, D60E, Q61D, H69K, T74A, L89M, I93L  
>08PR050350| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMSLPGKWKPKMIGGIGGFIKVREYE
DILIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215V, K219E V106M, Y188L Y181YH K20R, V35T, E36A, T39D, V60I, S68SG, T69TN, D121H, K122E, K166KR, K173KN, D177E, V189VI, T200A, Q207A, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, V317A, G335D Y232H
>08PR050350| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPI
FAIKKKNGNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRNQNPEIVI
HQYVDDLLIGSDLEIGQHRAKIEELRAHLLKWGFVTPDEKHQKEPPFLWMGHELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQD

References
Author Title Citation
Waleria-Aleixo, A Drug resistance mutation profile and accumulation kinetics in human immunodeficiency virus-positive individuals infected with subtypes B and F failing highly active antiretroviral therapy are influenced by different viral codon usage patterns. AAC, 2008