Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16103 | CA38333 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 35 |
| 2 | ABC+D4T+NVP | 70 |
| 3 | 3TC+ABC+D4T+NVP | 5 |
| 4 | 3TC+ABC+NVP | 102 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, V75I, F77L, F116Y, K219E | K103N, Y181I | E138EAKT | S68G, T69N, K122E, I142IM, S162C, R211A, F214L, A272P | V179N |
| >CA38333| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDGNKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEDFRKYTAFTIPSINNTTPGMRYQYNVLPMGWKGSPAIFQCSMTKILEPFRKQNPDINI IQYVDDLYVGSDLEIGQHRTKIEELRQHLLAWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13IV, K14KR, L63A, A71T, I72T, I93L |
| >CA38332| codons 1-99 PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIAIEICGHKTTGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |