Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16097 | CA38320 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36L, N37S, R57K, L63A, I72V |
| >CA38320| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVKQYD QIAIEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| R83K, D121H, K122E, S162D, K166R, Q197QE, T200TA, I202IV, R211K, V245E, E248ED, S251SI, Q278H, S322T, T377K, T386I, E399D, V435E, N447S, D460N, S519N, K530R |
| >CA38321| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTRILEPFRKQNPDIVI YQYMDDLYVGSDLEIGEHRAKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPDKDIWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKIAKESIVIWGKIPKFKLPIQKETWDAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIEGAETFYVDGAASRETKLGKAGYVTNRGRQKVVSLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |