<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08PR050313 08PR050313 Brazil 2005 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, L90M L33F, G73GA L10V, I13IV, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, Q61N, L63P, E65ED, C67CY, A71T, I72T, I85V  
>08PR050313| codons 1-99
PQITLWQRPVVTVKVGGQLTEALLDTGADDTVFEDINLPGKWKPKLIGGIGGFIRVKQYD
NIPIDIYGHKTTATVLVGPTPVNIVGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   E28K, K32E, V35T, T39K, D123E, I135T, I142T, K173A, Q174K, T200A, Q207A, R211K, F214FL, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297T, E328D  
>08PR050313| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIADIQKQGQG

References
Author Title Citation
Waleria-Aleixo, A Drug resistance mutation profile and accumulation kinetics in human immunodeficiency virus-positive individuals infected with subtypes B and F failing highly active antiretroviral therapy are influenced by different viral codon usage patterns. AAC, 2008