<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08RJ060604 08RJ060604 Brazil 2006 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, M46I N88D L10V, G16Q, E35D, M36V, P39T, R41K, K43R, R57K, D60E, Q61N, T74S, L89M  
>08RJ060604| codons 1-99
PQITLWQRPVVTIKIQGQLKEALLDTGADNTVLEDVNLTGKWRPKIIGGIGGFIKVKQYE
NILIEICGHKAIGSVLVGPTPVNIIGRDMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215Y       V35T, T39A, E44A, D86E, W88C, S117A, V118I, I135V, S162D, E169D, K173T, Q174K, I178L, E203EDV, Q207DE, H208Y, R211K, F214L, H221HY, V245Q, E248D, A272P, T286A, A288AT, E291D, V292I, I293V, E297A, V317A, Q330R  
>08RJ060604| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKAGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQEFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFAIPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILDPFRTKNPDLVI
YQYMDDLYVGSDLEIGQHRTKIDELREYLLKWGLYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTAEAE
LELAENREILKEPVHGAYYDPSKDLIAEIRKQGQG

References
Author Title Citation
Waleria-Aleixo, A Drug resistance mutation profile and accumulation kinetics in human immunodeficiency virus-positive individuals infected with subtypes B and F failing highly active antiretroviral therapy are influenced by different viral codon usage patterns. AAC, 2008