<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08RJ060595 08RJ060595 Brazil 2006 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46L, I54V, V82VA, L90M   L10LI, K14R, I15V, K20KR, E35D, M36I, I62V, L63P, A71V, I85V, L89I  
>08RJ060595| codons 1-99
PQITLWQRPIVTIRVGGQLREALLDTGADDTILEDINLPGRWKPKLIGGIGGFVKVRQYD
QVPIEICGHKVIGTVLVGPTPANIVGRNIMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R K219Q L100I, K103N, G190GRS   V35L, T39A, S48T, T69TN, V90VI, K122E, I135T, Q174R, I202V, E203K, Q207E, R211A, F214L, L228LH, V245M  
>08RJ060595| codons 1-263
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAEMEKEGKITKIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI
YQYMDDLYVRSDLEIGQHRTKVKELREHLLAWGLTTPDQKHQKEPPFHWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGK

References
Author Title Citation
Waleria-Aleixo, A Drug resistance mutation profile and accumulation kinetics in human immunodeficiency virus-positive individuals infected with subtypes B and F failing highly active antiretroviral therapy are influenced by different viral codon usage patterns. AAC, 2008