Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14297 | CA38210 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | 3TC+AZT | 22 |
| 3 | 3TC+AZT+IDV | 52 |
| 4 | 3TC+DDC+NFV | 31 |
| 5 | D4T+DDI+DLV | 78 |
| 6 | ABC+APV+D4T+DDI | 186 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IL | K43T | L10I, I15V, K20E, E34K, E35ED, M36I, I62T, L63P, A71V, I93L |
| >CA38210| codons 1-99 PQITLWQRPIVTIKVGGQLEEALLDTGADDTVLKDINLPGRWTPKMIGGIGGFLKVRQYD QTPIEICGHKVIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74LI, L210W, T215Y | K20R, K32E, V35L, T39D, E40F, R83K, V90I, V118I, K122E, T139K, K173T, I178FL, G196E, Q207E, H208Y, R211RK, V245E, E297A |
| >CA38211| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIEALLEICDFLEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKIVDFRELNKKTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDLVI YQYMDDLYVGSDLEIEQHRTKIEELREYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTAEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |