<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA14242 CA38203 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 Unknown 52
2 3TC+APV+DDI+EFV+RTV+SQV+TDF 22
3 None 22

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y K219Q K103KN, Y181C, G190GA A98AG V35VE, T39TA, K102KQ, K122E, D123N, G196E, E203K, Q207E, H208HY, K223KE, L228H, A272P E40E*DY
>CA38203| codons 1-300
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAYLEKEGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKQNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIEQHRTKIKELREYLWRWGFYTPDQKHQEEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82T, L90M L10F K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63P, A71V, I85V  
>CA38202| codons 1-99
PQITLWQRPFVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVKQYD
QVPIEICGHKVIGTVLVGPTPTNIVGRNLMTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005