Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14242 | CA38203 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+APV+DDI+EFV+RTV+SQV+TDF | 22 |
| 3 | None | 22 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | K219Q | K103KN, Y181C, G190GA | A98AG | V35VE, T39TA, K102KQ, K122E, D123N, G196E, E203K, Q207E, H208HY, K223KE, L228H, A272P | E40E*DY |
| >CA38203| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAYLEKEGKISKIGPENPYNTPV FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKQNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIEQHRTKIKELREYLWRWGFYTPDQKHQEEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, L90M | L10F | K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63P, A71V, I85V |
| >CA38202| codons 1-99 PQITLWQRPFVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVKQYD QVPIEICGHKVIGTVLVGPTPTNIVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |