Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9986 | CA38184 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 31 |
| 2 | DDI | 13 |
| 3 | 3TC+AZT+IDV | 383 |
| 4 | 3TC+EFV+LPV+TDF | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | V11I, L24I, Q58E | L10I, I15V, I62V, L63P, A71V, I72T |
| >CA38184| codons 1-99 PQITLWQRPIITIKVGGQLKEALIDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVREYD QVPIEICGHKVTGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219E | T39TA, S68G, D123E, I142IT, S162CY, D177E, I178L, G196K, R211G, V245E, A272P, K277R, E297A |
| >CA38185| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKNGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPELVI YQYVDDLYVGSDLEIKQHRTKIEELRQHLWGWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTAEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |