Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CH001546 | CA38115 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 61 |
| 2 | AZT+DDI+SQV | 26 |
| 3 | 3TC+AZT+SQV | 26 |
| 4 | 3TC+AZT+NFV | 48 |
| 5 | 3TC+ABC+NVP | 51 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, T215F | K219Q | G190A | K20R, K102R, K103R, K104KR, K122KE, D123DE, V179I, G196E, T200A, H208HY |
| >CA38115| codons 1-249 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRRRSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVASDLEIEQHRAKIEELRQYLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10LF | R41K, D60DE, I62V, L63AT, V77VI, I85IV |
| >CA38114| codons 1-98 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE QVTIEICGHKAIGTVLIGPTPVNIVGRNLMTQIGCTLN |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |