<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA4873 CA38080 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 230
2 DDI NA
3 Unknown NA
4 3TC+ AZT+ IDV 170
5 RTV+ 3TC+ AZT+ IDV 34
6 D4T+ DDI+ LPV 128
7 Unknown 14

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M V11I, L33F, G73S L10V, L19I, M36L, N37D, K55R, I62V, L63P, C67FL, A71V, I72L  
>CA38080| codons 1-99
PQITLWQRPVITIKIGGQIKEALLDTGADDTVFEELDLPGRWKPKLIGGIGGFVRVRQYD
QVPIEILGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, T215F K219Q K101E   E28EA, E53EG, V60VI, A98S, D123E, I135T, S162Y, V179VI, I195T, T200A, V245K, A272P, A288S, I293IV  
>CA38081| codons 2-299
ISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALVEICTEMEKEGKISKIGPGNPYNTPIF
AIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLEKKKSVTVLDVGDAYFSVPLD
KEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIIIY
QYMDDLYVGSDLETGQHRAKIEELRQHLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWTV
QPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVVPLTEEA

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005