Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1113 | CA38067 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 17 |
| 2 | 3TC+AZT+SQV | 26 |
| 3 | 3TC+AZT+NVP | 8 |
| 4 | 3TC+D4T+NFV | 27 |
| 5 | 3TC+D4T+RTV+SQV | 134 |
| 6 | 3TC+ABC+EFV | 136 |
| 7 | Unknown | 14 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, Y115F, M184V | L100I, K103N | K11KR, K122E, I135T, I142V, K173KE, D177G, F214L, H221Y, V245T, I293V, E297K |
| >CA38067| codons 1-300 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAFFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFREQNPGIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKYQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | Q58E, G73GS | T12M, K20R, E35D, M36I, N37DE, R57K, I62V, L63P, A71V |
| >CA38066| codons 1-99 PQITLWQRPLVMIKIGGQLREALLDTGADDTVLEDIELPGRWKPKMIGGIGGFIKVKEYD QVPIEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |