Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1113 | CA38064 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 17 |
| 2 | 3TC+AZT+SQV | 26 |
| 3 | 3TC+AZT+NVP | 8 |
| 4 | 3TC+D4T+NFV | 27 |
| 5 | 3TC+D4T+RTV+SQV | 127 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | Q58E, G73S | T12M, I13V, K20R, E35D, M36I, N37D, R57K, I62V, L63P, A71V |
| >CA38064| codons 1-98 PQITLWQRPLVMVKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVKEYD QVPIEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLN |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K122KE, I135T, I142V, D177EG, F214L, V245T |
| >CA38065| codons 1-249 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPGIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |