<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA8360 CA38016 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 21
2 SQV+ AZT+ 3TC 115
3 ABC+ 3TC+ NFV+ AZT 132
4 LPV+ AZT+ ABC+ 3TC 76
5 Unknown 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M G73GS, L89LV L10I, T12S, I13V, I15IV, L19Q, K20I, M36I, I62IV, L63P, A71T, I72IL  
>CA38016| codons 1-99
PQITLWQRPIVSVKVGGQQIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFVKVRQYD
QVPIEICGHKTLSTVLVGPTPANIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, M184V, L210W, T215Y       E6D, K43E, E44ED, K49R, V60I, S68SG, V118I, I135T, S162D, G196E, T200IR, E203EK, Q207DE, R211K, L228H, A272P, I293IV, E297R  
>CA38017| codons 1-300
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISRIGPENPYNTPI
FAIKKKNGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRRKIKELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTREAE

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005