Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5015 | CA37876 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 22 |
| 2 | D4T | 31 |
| 3 | 3TC+AZT | 22 |
| 4 | 3TC+AZT+IDV | 200 |
| 5 | 3TC+AZT+IDV+RTV | 146 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82T, L90LM | L10I, I13V, K20I, E35D, M36I, N37D, R57K, L63P, I64V, I66F, A71V |
| >CA37876| codons 1-99 PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFAKVKQYD QIPVEFCGHKVIGTVLVGPTPTNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K20R, T69S, K122E, I142V, V245KR, S251I, A272P |
| >CA37877| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIRLPEKDIWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |