Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4022 | CA37873 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 26 |
| 2 | 3TC+AZT+RTV | 31 |
| 3 | D4T+IDV+NVP | 109 |
| 4 | 3TC+APV+D4T | 223 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, V75VIM, M184V, L210W, T215Y | A98G | V35KM, T39TA, K43N, E44ED, E53EQ, P55PS, V60VI, S68SG, V118I, K122E, I135T, G196GE, E203K, Q207E, H208HY, R211K, K223KE, A272P, I293V |
| >CA37873| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELENDGKISKIGPQNSYNTPI FAIKKKNGTKWRKLMDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIKELREYLWKWGFYTPDKKHQEEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I50V, I54V, V82VA | L33F | L10I, I13IV, K20R, E35D, M36I, N37D, I62V, L63P, A71V, I72V |
| >CA37872| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADDTVFEDIDLPGRWKPKMIGGVGGFVKVRQYD QVPIEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |