Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7065 | CA37857 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+SQV | 22 |
| 2 | AZT+IDV | 35 |
| 3 | 3TC+D4T+IDV | 191 |
| 4 | D4T+DDI+EFV | 125 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69TADN, L74LV, L210W, T215Y | L100I, K103N | K43E, E44A, V60VI, V118I, I135T, D177E, I178M, G196GE, Q207K, R211T, K223KQ, L228R, V245T, A272P, K277R, E297K, K311R, Q334Y, M357V, T403M, T450S, L452A, V467I, L491S, Q509H |
| >CA37857| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPI FAIKKKDSNKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIEQHRTKIEELRKHLWTWGFYTPDKKHQQEPPFRWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGYGQWTYQIYQEPFKNLKTGKYARVRGA HTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRESKAGKAGYVTDRGRQKVISLTDTTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGIIQAHPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A, L90M | L10I, R41K, K55R, D60E, Q61E, I62V, L63P, A71T, I72R, V77I, I85V, I93L |
| >CA37856| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIRVRQYE EVPIEICGHKTRGTVLIGPTPANIVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |