Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5551 | CA37828 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 87 |
| 2 | None | 15 |
| 3 | 3TC+AZT+NFV+RTV | 76 |
| 4 | 3TC+AZT+NFV | 78 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215F | K219E | E28A, K32Q, V35I, D123E, I135T, I142V, I167IV, D177E, V179I, T200IM, I202V, H208HY, R211K, L228H, K277R, T286A, A288T, I293IV, E297A |
| >CA37828| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIQALIEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKVLEPFRKQNPEIII YQYVDDLYVGSDLEIGQHRMKVEELRQYLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKTLTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, N88S, L90LM | Q58E | K20L, I62V, L63P, A71T, T74S, V77I |
| >CA37827| codons 13-99 IKIGGQLLEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVREYDQVPIEICGHKTI GSVLIGPTPVNIIGRSLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |