Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1337 | CA37752 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 31 |
| 2 | 3TC+D4T+RTV | 12 |
| 3 | 3TC+D4T+IDV | 41 |
| 4 | AZT+DDI+NFV | 34 |
| 5 | 3TC+AZT+RTV+SQV | 3 |
| 6 | 3TC+AZT+NFV+SQV | 20 |
| 7 | 3TC+ABC+AZT+ADV+EFV+NFV+SQV | 19 |
| 8 | Unknown | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54V, V82A, L90M | L33F, F53L, G73GS | I13V, I15V, L19I, K20M, E35D, M36I, L63P, A71V |
| >CA37752| codons 1-99 PQITLWQRPLVTVKVGGQIMEALLDTGADDTIFEDINLPGRWKPKIVGGIGGLVKVRQYD QIPIEICGHKVISTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K103N | V35MT, K122E, D123NS, I135T, I142V, I178IM, A272P, A288S |
| >CA37753| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVIPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |