Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7101 | CA37746 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 139 |
| 2 | 3TC+AZT+RTV+SQV | 299 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48T, I54V, V82A, I84V | L24I | L10I, I13V, G16E, K20I, L63T, I72T, T74S, V77I, L89M, T91A |
| >CA37746| codons 1-99 PQITLWQRPIVTVKIEGQLIEALIDTGADDTVLEEMNLPGRWKPKLITGIGGFVKVRQYD QITIEICGHKATGSVLIGPTPANVIGRNMLAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K43E, E44A, V118I, D121Y, K122E, I135T, S162C, G196E, E203K, Q207E, H208Y, R211K, K223Q, L228HR, A272P, T286A, E297P | I167M |
| >CA37747| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKMLEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIKELREYLWKWGFYTPDKKHQQEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTPEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |