Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8001 | CA37734 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | 3TC+AZT | 26 |
| 3 | 3TC+AZT+IDV | 261 |
| 4 | 3TC+AZT+LPV+NVP | 112 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, V82VA, L90M | L10F, F53L | L19I, K20T, M36I, L63P, I64V, A71AV, I72V, I93IL |
| >CA37734| codons 1-99 PQITLWQRPFVTIKIGGQITEALLDTGADDTILEEINLPGRWKPKIVGGIGGLIKVRQYD QIPVEICGHKVVGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184V | T215V, K219Q | K103N | P4PS, E6D, E28EGKR, K101KQ, T200I, I202V, E203Q, Q207D, T286A, I293IV, E297A |
| >CA37735| codons 1-300 PISSIDTVPVKLKPGMDGPKVKQWPLTREKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRIKVQELRDHLLRWGFVTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTAEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |