Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1601 | CA37656 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ DDC+ AZT | 17 |
| 2 | IDV+ D4T+ 3TC | 87 |
| 3 | EFV+ DDI+ ADV | 35 |
| 4 | ABC+ D4T+ RTV+ IDV | 130 |
| 5 | TDF+ LPV+ DDI | 29 |
| 6 | Unknown | 20 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, G73T | I13IM, K20I, M36MI, N37D, I62V, L63P, C67F, A71T, I72T, I93L |
| >CA37656| codons 1-99 PQITLWQRPFVTMKIGGQLIEALLDTGADDTVLEEIDLPGRWKPKIIGGIGGFVKVRQYD QVPIEIFGHKTTTTVLVGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DGNS, T69TADN, L210W, T215Y | K219R | K20KR, V35M, T39A, K43Q, E44D, V60VI, V118I, K122E, G196E, T200A, E203D, L205F, Q207E, H208Y, R211K, D218E, D250DE, A272P, K281R, I293IMV, E297R |
| >CA37657| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEQDGKISKIGPENPYNTPI FAIKKKSSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRAKIDEFREYLWKWGFYTPERKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVVPLTREAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |