Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| D | DPre | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ D4T+ IDV | NA |
| 2 | None | 2 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K20R, V35I, D121H, K122E, Q174H, V179I, D218DE, Q269X, A272P, K277R, Q278QE | Q258K, V276G |
| >DPre| codons 1-280 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKHNPDIII YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPEKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIKKLVGKLNWASXIYPGIKGRELC |
References
| Author | Title | Citation |
| Barditch-Crovo, P | Phase I/II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. | AAC, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |