<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47A, L90M L10F, L89V T4A, I13V, K20T, L33V, I62V, L63P, H69Y, A71V, I93L  
>175848| codons 1-99
PQIALWQRPFVTVKIGGQLTEALLDTGADDTIVEEMNLPGRWKPKIAGGIGGFIKVRQYD
QVPIEICGYKVIGTVLVGPTPVNIIGRNVMTQLGCTLNF

References
Author Title Citation
Kagan, RM Structural analysis of an HIV-1 protease I47A mutant resistant to the protease inhibitor lopinavir. Protein Sci, 2005
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005