<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BM-51 BM-51 France 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI 52
2 D4T+DDI 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67~, K70R, T215F T69G, K219E     L109LV, G196R, T200A, I202T, R211K, L228H  
>BM-51| codons 31-254
IKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKK~SGRWRKLVDFRELNKRTQDFWEV
QLGIPHPAGLKKKKSVTVVDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLP
QGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIRQHRAKTEELRQHLL
KWGFFTPDEKHQKEPPFHWMGYELHPDKWTVQPIVLPEKDSWTV

References
Author Title Citation
Masquelier, B Genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 variants with insertions or deletions in the reverse transcriptase (RT): multicenter study of patients treated with RT inhibitors. AAC, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005