<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BM-3 BM-3 France 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 RTI NA
2 NVP+ 3TC+ AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69D_D, K70R, M184I K219Q Y181C   K49R, K64N, I135L, I178M, E203K, Q207E, D218E  
>BM-3| codons 23-240
QWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPVFAINKKDSDRWRKLVDFRELNK
RTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNETPGI
RYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVICQYIDDLYVGSDLEIGQHRTKI
KELREHLLRWGFTTPEQKHQKEPPFLWMGYELHPDKWT

References
Author Title Citation
Masquelier, B Genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 variants with insertions or deletions in the reverse transcriptase (RT): multicenter study of patients treated with RT inhibitors. AAC, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005