<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA220 CTLA220 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, T215Y   Y181C F227L V35T, T39N, V60I, V90I, V106I, D121Y, K122E, D123E, I135R, S162A, K173A, D177E, V179I, Q197K, T200A, I202V, Q207G, R211K, L228V W229G
>CTLA220| codons 21-235
VKQWPLTEEKIKALTEICNELEKEGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFREL
NKRTQDFWEIQLGIPHPAGLKKKKSITVLDVGDAYFSVPLYEEFRKYTAFTIPSRNNETP
GIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPEIIICQYVDDLYVGSDLEIGKHRA
KVEELRGHLLKWGFYTPDKKHQKEPPLVGMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015