<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA328 CTLA328 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, M184V, T215F K219Q K101E, V106M, G190A V108I, F227L V35T, T39E, V60I, I94L, D121HY, K122E, I135T, E138Q, K173AT, Q174QK, D177E, T200A, E203D, Q207A, R211K, F214L, H221HY  
>CTLA328| codons 21-235
VKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKLVDFREL
NKRTQDFWEVQLGLPHPAGLEKKKSMTILDVGDAYFSVPLYEDFRKYTAFTIPSTNNQTP
GIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVIYQYVDDLYVASDLEIGQHRA
KIDELRAHLLKWGLFTPDQKYQKEPPLLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015