<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA409 CTLA409 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115YF, M184V   K103KN, V106M, Y181C F227L T27S, V35T, T39E, V60I, D121Y, K122E, I135R, I142V, K173A, Q174K, D177E, T200A, Q207N, R211K  
>CTLA409| codons 21-235
VKQWPLSEEKIKALTEICEEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKVVDFREL
NKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAFFSVPLYEDFRKYTAFTIPSRNNETP
GVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVICQYVDDLYVGSDLEIGQHRA
KIEELRNHLLKWGFTTPDKKHQKEPPLLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015