<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA355 CTLA355 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, L210W, T215Y   Y181C, M230L A98AG, V108I V35T, T39D, E44D, S48T, V60I, V118I, D121Y, K122E, I135T, S162A, T165I, K173A, Q197K, T200A, E203EK, Q207E, R211K, D218E, L228R  
>CTLA355| codons 21-235
VKQWPLTEEKIKALTEICDEMEKDGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFREL
NKRTQDFWEVQLGIPHPGGLKKKKSVTILDVGDAYFSIPLYEDFRKYTAFTIPSTNNETP
GIRYQYNVLPQGWKGSPAIFQASMIKILEPFRAQNPDIVICQYVDDLYVGSDLEIGKHRA
KIKELREHLWKWGFYTPEKKHQKEPPFRWLGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015