<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA482 CTLA482 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y K219N   V108I K32E, V35T, E36A, T39E, E44D, V60I, I135R, E138Q, K173A, D177E, I178L, Q197K, T200A, E203K, Q207E, R211K, H221Y  
>CTLA482| codons 21-235
VKQWPLTEEKIEALTAICEELEKDGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFREL
NKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPLDKDFRKYTAFTIPSRNNQTP
GIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPELVIYQYVDDLYVGSDLEIGKHRA
KIKELREHLWKWGFYTPDNKYQKEPPFLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015