<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA386 CTLA386 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, Y181C, G190A   T27S, V35T, E36A, T39D, S48T, V60I, V90I, D121H, K122E, I135T, S162H, T165I, K173A, Q174K, D177E, T200A, Q207E, F214L, L228R  
>CTLA386| codons 21-235
VKQWPLSEEKIKALTAICDEMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFREL
NKRTQDFWEIQLGIPHPAGLEKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETP
GIRYQYNVLPQGWKGSPAIFQHSMIKILEPFRAKNPEIVICQYVDDLYVASDLEIGQHRA
KIEELREHLLRWGLTTPDKKHQKEPPFRWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015