Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TVGG19 | TVGG19 | Brazil | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 47 |
| 2 | D4T+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V | M16V, K122E, D123N, I135T, D177E, T200E, I202V, R211K, V245M, A272P, V276I, I293V |
| >TVGG19| codons 1-324 PISPIETVPVKLKPGVDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHREKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, Q18E, E35D, L63P, I93L |
| >TVGG19| codons 1-99 PQITLWQRPVVTIKIGGELKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Brindeiro, PA | Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. | J Clin Microbiol, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |