<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA490 CTLA490 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74I, M184V, T215Y   K103N, Y181C, G190A F227L V35T, E36A, T39D, E44D, V111I, D121H, K122E, K166R, K173A, T200A, E203D, Q207E, L210S  
>CTLA490| codons 21-235
VKQWPLTEEKIKALTAICDEMEKDGKISKIGPENPYNTPVFAIKKKDSTKWRKIVDFREL
NKRTQDFWEVQLGIPHPAGLKKNKSVTVLDIGDAYFSVPLHEDFRKYTAFTIPSINNETP
GIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPDIVICQYVDDLYVASDLEIGQHRA
KIDELREHLSRWGFYTPDKKHQKEPPLLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015