Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TVGG8 | TVGG8 | Brazil | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 108 |
| 2 | D4T+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Y115F, Q151M | V75I, F77L, F116Y, K219E | K20R, S68G, I135T, R172K, D177E, T200A, R211K, V245M, A272P, Q278H, I293V, E297A |
| >TVGG8| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKRKDGTRWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFKKQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G17D, E35D, D60E, L63P |
| >TVGG8| codons 1-99 PQITLWQRPLVTIKIGDQLKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYE QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Brindeiro, PA | Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. | J Clin Microbiol, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |