<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA489 CTLA489 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70E D67G V106M, G190A F227L V35T, T39E, S48T, V60I, D121H, K122E, D123E, I135T, I142V, S162A, K173A, D177E, T200A, Q207A  
>CTLA489| codons 21-235
VKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPIFAIKKKGSTEWRKLVDFREL
NKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPLHEEFRKYTAFTIPSTNNETP
GVRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPEIVIYQYMDDLYVASDLEIGQHRA
KIEELRAHLLRWGFTTPDKKHQKEPPLLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015