<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CTLA254 CTLA254 India 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, M184V A62V, V75I K103NS, V106M F227L V35T, E36A, T39D, S48T, V90I, D121Y, K122E, I135T, S162A, K173A, D177E, T200A, Q207G, R211K  
>CTLA254| codons 21-235
VKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPVFVIKKKNSTEWRKLIDFREL
NKRTQDFWEIQLGIPHPAGLKKSKSMTVLDVGDAYFSVPLYEDFRKYTAFTIPSTNNETP
GIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRA
KIEELRGHLLKWGFTTPDKKHQKEPPLLWMGYELH

References
Author Title Citation
Saravanan, S Differences in evolution of HIV-1 subtype C reverse transcriptase between children and adults likely explained by maturity of cytotoxic T-lymphocyte responses. ARHR, 2015