Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| URTR35 | URTR35 | Uruguay | 1999 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, R57K, Q61N, I93L |
| >URTR35| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, I135V, I142V, R211A, A272P, E297K, Q334L, K366R, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, N447S, L452K, R463K, V466A, S468P, D471E, T477A, Q480H, H483Q, L491S, L503I, S519N, A534S, V559I |
| >URTR35| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLAWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVRQLTEAVQKITTESIVIWGKTPKFRLPILKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPIAGAETFYVDGAASRETKKGKAGYVTDRGKQKAVPLTETTNQKAELH AIQLALQDSGSEVNIVTDSQYAIGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, S17N, I72V, I84L, L101I, K111R, S119P, T122S, T124A, T125A, I135V, K136Q, G163H, V201I, T218I, S230N, L234V, D256E | S283G |
| >URTR35| codons 1-288 FLDGIDKAQEDHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVRTIHTDNGPN FSSAAVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIHQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDNRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Carr, JK | Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America. | AIDS, 2001 |