Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| URTR23 | URTR23 | Uruguay | 1999 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, E35D, M36I, R41K, R57K, Q61N |
| >URTR23| codons 1-99 PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39M, D123E, I135V, Q197K, F214L, E248D, L260V, A272P, I274V, T286A, E297K, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452I, V466A, S468P, D471E, T477A, H483Q, L491S, S519N, A534S, V559I |
| >URTR23| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGKHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKVVGKLNWASQIYPGVKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKITTESIVIWGKTPKFRLPILKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPIAGAETFYVDGASNRETKIGKAGYVTDRGRQKAVPLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| G163K | S17N, L45V, I84L, S119T, T122S, T124A, T125A, K136Q, V201I, A205S, T218I, L234V, D256E | S283G |
| >URTR23| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQVKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYLEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGTN FSSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIKQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTKELQKQIIKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Carr, JK | Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America. | AIDS, 2001 |