Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ARCH003 | ARCH003 | Argentina | 2000 | HIV1 | CRF12_BF | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12I, I15V, E35D, M36I, R41K, R57K, Q61N, L63Q, I72T |
| >ARCH003| codons 1-99 PQITLWQRPLVIIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NIQIEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, D123E, I135V, D177N, I202V, L228H, P243A, V245M, I293V, P294T, E297R, K311R, I329V, G359S, A371V, T377L, S379G, T386I, A400T, E404D, K431T, S468P, H483Y, Q524E |
| >ARCH003| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLRWGFTTPDKKHQKEPPFHWMGYELHPDKWT VQAIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVTLTREAE LELAENREILREPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLKTGKYARMRSA HTNDVKQLTEVVQKIALEGIVIWGKIPKFKLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLETEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEELIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V151I | E11D, S17N, I72V, I84L, L101I, T125A, K136Q, V165I, V201I, A205S, K211R, K215N, T218I, L234V, D256E | S283G |
| >ARCH003| codons 1-288 FLDGIDKAQEDHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTAVKAACWWAGIQQEFGIPYNPQSQGVIESMNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQNQIIKIQNFRVYYRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Carr, JK | Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America. | AIDS, 2001 |