<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CM53657 CM53657 Cameroon 1997 HIV1 F PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, L63P, H69Q, L89M  
>CM53657| codons 1-99
PQITLWQRPLVTIKVEGQLREALLDTGADDTVLEDINLSGKWKPRMIGGIGGFIKVRQYD
QIPIEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        P4S, V35T, D123E, K173V, Q174K, D177E, Q207E, P243A, V245Q, E248D, D250S, A272P, K275R, Q278H, T286A, E291D, I293V, E297V, L303M, I329V, Q334H, G335D, F346H, M357R, G359S, A371V, S379G, T386V, K390R, A400T, K431T, V435L, L452I, S468P, D471E, L491S, Q509H, S519N, K527Q, K530R, A534S  
>CM53657| codons 1-560
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKSSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGAKALTDVVPLTVEAE
LEMAENREILKEPVHGVYYDPSKDLIAEVQKQGHDQWTYQIYQEPHKNLKTGKYARRRSA
HTNDVKQLTEVVQKIATEGIVIWGKVPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPILGAETFYVDGAANRETKIGKAGYVTDRGRQKVVPLTETTNQKTELQ
AIHLALQDSGSEVNIVTDSQYALGIIQAHPDKSESELVNQIIEQLIQKERVYLSWVPAHK
GIGGNEQVDKLVSAGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E S283G
>CM53657| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIIHTDNGSN
FTSTVVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Carr, JK The AG recombinant IbNG and novel strains of group M HIV-1 are common in Cameroon. Virology, 2001