Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR68 | DR68 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ RTV | 104 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, Q151M, M184V | A62V, V75I, F77L, F116Y | V35T, T39EK, E40EK, S48T, S68G, T69TI, K122E, D123S, S162C, K166KR, K173T, Q174K, I178IL, G196E, T200A, I202IV, Q207E, F214L, V245Q, E248D, A272P, E291D, V292VI, I293V, E297K | E194AT |
| >DR68| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEKMEKEGKITKIGPENPYNTPV FVIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQCSMTRILEPFRTKNPDLVI YQYVDDLYVGSDLAIEQHRAKVEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L10V, T12S, I15V, L19I, E35ED, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L |
| >DR68| codons 1-99 PQITLWQRPVVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYE EIPIEICGKKAIGTVLVGPTPANIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |