Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR61 | DR61 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | NA |
| 2 | D4T+ DDI+ NFV+ RTV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VL, L90LM | T12TS, I13IV, I15V, L19M, K20R, M36I, N37D, R41K, H69K, L89M, I93L |
| >DR61| codons 1-99 PQITLWQRPLVSVKVGGQMREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPLNIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML | V35T, E36A, T39E, S48T, W88WC, K122E, D123DG, I135IV, K166R, K173A, Q174K, D177E, G196R, T200V, Q207D, T215X, V245Q, D250N, A272P, K277R, T286A, E291D, V292I |
| >DR61| codons 1-309 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEELEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIRQHRVKIEELRDHLLRWGFXTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKNSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREI |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |