<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR59 DR59 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M A62V, V75I, F77L, F116Y     T39E, S68G, A98S, K122A, S162X, S163ST, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, Q278H, I293V, S322A, Q334X  
>DR59| codons 37-334
ICEEMEKEGKISKIGPENPYNTPVFVIKRKDGTKWRKLIDLRELNKRTQDFWEVQLGIPH
PSGLKKKKSVTVLDVGDAYYSVPLDADFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGS
PAIFQXTMTKILEPFRAKNPELVIYQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTT
PDKKHQKEPPFLWMGYELHPDKWTVQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKV
KHLCKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPAKDLIAEIQKQGX

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93L L90W
>DR59| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGSVLVGPTPVNIIGRNMWTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008