<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR58 DR58 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ NFV+ AZT NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N   T12S, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45Q, I64V, H69K, L89I, I93L  
>DR58| codons 1-99
PQITLWQRPLVSVKVGGQIREALLDTGADNTVLEDINLPGKWKPQMIGGIGGFIKVRQYD
QILVEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     V108I, E138K V35M, E36EA, T39E, S48T, D123E, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, V317A, S322SA  
>DR58| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DKEFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPAKDLIAEIQKQG

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008