Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR56 | DR56 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | NA |
| 2 | EFV+ D4T+ DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L100LI, K103N | S3I, E28K, K32E, V35T, E36A, T39E, S48T, T69TN, L74X, K101X, K122E, D123N, I135L, K173A, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248DN, S251C, A272P, K277R, T286A, E291D, V292I, Q334D |
| >DR56| codons 1-335 PIIPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSNKWRKXVDFRELNKRTQDFWEVQLGIPHPAGIXKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDCWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L5F, T12S, I15V, L19I, M36I, R41K, Q61E, L63X, H69K, T74S, L89M, I93L |
| >DR56| codons 1-99 PQITFWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD EIXIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |