<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR55 DR55 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC+ RTV 104

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V35T, T39K, S48T, D86N, K122E, D123S, I142IT, K173T, Q207A, V245C, A272P, T286A, E291D, V292I, I293V  
>DR55| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQNFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPICLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L23LI T12S, I15V, G16GE, L19I, K20R, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
>DR55| codons 1-99
PQITLWQRPLVSIKVEGQIREAILDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVRQYD
QIVIEICGKKAIGSVLVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008