Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR54 | DR54 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NFV | NA |
| 2 | RTV+ AZT+ 3TC | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19T, M36L, R41K, L63T, H69K, T74S, L89M, I93L, F99FL |
| >DR54| codons 1-99 PQITLWQRPLVTIKIGGQTKEALLDTGADDTVLEELNLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNL |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | S3SC, V35T, E36A, T39E, S48T, E53D, K122E, D123G, I135IT, S162SC, K173A, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, S322A, D324E | P1PA |
| >DR54| codons 1-333 AICPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPDNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPELVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKELIAEIQKQG |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |